Bimonthly assessment January
a) Problem representation : 26yr old female with k/c/o SLE Polyarthritis with head ache since 8 days and fever, vomtings since 4 days and altered sensorium since 2 days with Euvolemic hyponatremia under evaluation. Anatomical localization: Brain. b) etiology: CVA , TB Meningitis , SLE vasculitis ,SIADH secondary to infection. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357611/( Bisphosphonate prophylaxis). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970554/(proton pump for corticosteroid ulcers) https://pubmed.ncbi.nlm.nih.gov/10067053/ ( TB Meningitis in SLE pts) C) Bisphosphonates were given to prevent osteoporotic fracture risk associated with using long-term steroids. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357611/ Bisphosphonate prophylaxi s d) Probable cause of normal CSF count in patients of Chronic meningitis is probably due to the use of steroids which caused immunosuppression and decreased inflammatory was the research question in the above thesis presentation